[et_pb_section fb_built=”1″ _builder_version=”3.22″ custom_padding=”28px|0px|0|0px|false|false”][et_pb_row _builder_version=”3.25″ custom_padding=”27px|0px|0|0px|false|false”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”3.27.4″ header_font=”||||||||” header_text_color=”#000000″ header_4_font=”|700||on|||||” header_4_text_align=”center” header_4_text_color=”#000000″ header_4_font_size=”19px” header_4_letter_spacing=”1px”]<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ specialty=”on” _builder_version=”3.22″ custom_padding=”24px|0px|25px|0px|false|false”][et_pb_column type=”3_4″ specialty_columns=”3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_row_inner _builder_version=”3.25″][et_pb_column_inner saved_specialty_column_type=”3_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_blurb title=”Editoral in Hungarian” url=”https:\/\/mppt.hu\/magazin\/pdf\/xx-evfolyam-2-szam\/szerk_lev_honlapra.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_max_width=”105%” content_max_width=”1100px” _builder_version=”4.6.6″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/xx-evfolyam-2-szam\/szerk_lev_honlapra.pdf” link_option_url_new_window=”on”]<\/p>\n
Prof Dr. G\u00e1bor Faludi\u00a0<\/p>\n
[\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ _builder_version=”3.22.2″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px”]<\/p>\n
T\u00e1rsas\u00e1gunk tiszt\u00faj\u00edt\u00f3 k\u00f6zgy\u0171l\u00e9s\u00e9t 2018. \u00e1prilis 23-\u00e1n tartottuk. Szomor\u00fa aktualit\u00e1s\u00e1t az adta, hogy tavaly j\u00faliusban meghalt Gaszner P\u00e9ter, aki 1980-t\u00f3l 37 \u00e9ven kereszt\u00fcl volt az \u00e1ltala alap\u00edtott
Pszichofarmakol\u00f3giai Egyes\u00fclet, jelenlegi nev\u00e9n Magyar Pszichofarmakol\u00f3gusok T\u00e1rsas\u00e1g\u00e1nak eln\u00f6ke. Eln\u00f6ks\u00e9ge alatt a T\u00e1rsas\u00e1g akt\u00edv szakmai k\u00f6z\u00e9leti tev\u00e9kenys\u00e9get fejtett ki, konferenci\u00e1kat szervezett,
tudom\u00e1nyos szaklapot jelentetett meg, melynek id\u00e9n a 20. \u00e9vfolyam\u00e1t forgathatjuk. A gazdas\u00e1gi v\u00e1ls\u00e1g, a gy\u00f3gyszeripart folyamatosan megszor\u00edt\u00f3 int\u00e9zked\u00e9sek \u00e9s a szakemberek elv\u00e1ndorl\u00e1sa k\u00f6vetkezt\u00e9ben
azonban az ut\u00f3bbi id\u0151ben mozg\u00e1ster\u00fcnk besz\u0171k\u00fclt, aktivit\u00e1sunk lelassult, p\u00e9ld\u00e1ul a hossz\u00fa \u00e9vekig sikerrel m\u0171k\u00f6d\u0151 tihanyi neuropszichofarmakol\u00f3giai kongresszusi sorozatunk megszakadt, szakla-
punkba \u2013 Neuropsychopharmacologia Hungarica \u2013 kevesebb bek\u00fcld\u00f6tt k\u00e9zirat \u00e9s kevesebb hirdet\u0151i t\u00e1mogat\u00e1s \u00e9rkezett.<\/p>\n
A t\u00e1rsas\u00e1gi tiszt\u00faj\u00edt\u00e1s teh\u00e1t nemcsak k\u00e9nyszer\u0171 szem\u00e9lycser\u00e9kr\u0151l sz\u00f3l, hanem meg\u00fajul\u00e1si sz\u00e1nd\u00e9kr\u00f3l, lend\u00fcletbe hoz\u00e1sr\u00f3l, a kor\u00e1bbi \u00e9rt\u00e9kek tov\u00e1bbvitel\u00e9r\u0151l \u00e9s \u00faj \u00e9rt\u00e9kek teremt\u00e9s\u00e9r\u0151l, ezek \u00e1tad\u00e1s\u00e1r\u00f3l.<\/p>\n
Elhat\u00e1roztuk, hogy \u00fajra\u00e9lesztj\u00fck \u00e9s megpr\u00f3b\u00e1ljuk ism\u00e9t \u00e9vente megrendezni Tihanyban a Magyar Neuropszichofarmakol\u00f3giai Kongresszust. Tervez\u00fcnk m\u00e9g workshopokat, \u00e9s a honlapon kereszt\u00fcl
megval\u00f3sul\u00f3 pszichofarmakol\u00f3giai konzult\u00e1ci\u00f3s lehet\u0151s\u00e9get is.
Magamat, mint \u00e9letkorban nem fiatal megv\u00e1lasztott eln\u00f6k\u00f6t, \u00e9s Kov\u00e1cs G\u00e1bor \u00fajrav\u00e1lasztott aleln\u00f6k\u00f6t lesz\u00e1m\u00edtva val\u00f3ban fiatal, akt\u00edv \u00e9s dinamikus tiszts\u00e9gvisel\u0151k fognak gondoskodni c\u00e9ljaink megval\u00f3s\u00edt\u00e1s\u00e1r\u00f3l Makkos Zolt\u00e1n f\u0151titk\u00e1r \u00e9s P\u00e9ter L\u00e1szl\u00f3 aleln\u00f6k szem\u00e9ly\u00e9ben. A T\u00e1rsas\u00e1g az eln\u00f6ks\u00e9gen k\u00edv\u00fcl \u00faj 13 tag\u00fa vezet\u0151s\u00e9get v\u00e1lasztott \u00e9s \u00e1talak\u00edtotta a T\u00e1rsas\u00e1g lapj\u00e1nak \u2013 Neuropsychopharmacologia
Hungarica \u2013 szerkeszt\u0151s\u00e9g\u00e9t is.<\/p>\n
Prof Dr. Faludi G\u00e1bor<\/p>\n
[\/et_pb_toggle][et_pb_blurb title=”Prediction of response to lamotrigine treatment in bipolar outpatients: a multicentric, 6-month, prospective, observational study” url=”https:\/\/mppt.hu\/magazin\/pdf\/xx-evfolyam-2-szam\/gonda_honlapra.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_max_width=”105%” content_max_width=”1100px” _builder_version=”4.6.6″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/xx-evfolyam-2-szam\/gonda_honlapra.pdf” link_option_url_new_window=”on”]<\/p>\n
X\u00e9nia Gonda and Zolt\u00e1n Rihmer <\/p>\n
[\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ _builder_version=”3.22.2″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px”]<\/p>\n
In case of a major depressive episode it is crucial to establish whether this is a depressive
episode in the course of a bipolar I or bipolar II disorder or a \u201ctrue\u201d unipolar major depression
which is possible through screening for lifetime manic or hypomanic episodes and can be
facilitated by the use of the Hypomania Checklist (HCL-32). In cases where (hypo)mania
is present in the anamnesis, mood stabilising treatment is warranted even in cases where
depressive symptoms predominate the clinical course. However, the association between
hypomania in the history and efficacy of mood stabilising lamotrigine treatment has not been
previously investigated. In our present study we aimed to analyse clinical and psychosocial
characteristics of HCL-32 identified lifetime \u201cupbeat\u201d periods, and to establish if there is an
association between baseline-assessed HCL-32 3rd part total scores and remission and relapse
rates during 6-month lamotrigine treatment. Our results indicate that baseline HCL-32 group
3rd part scores showed a trend for a moderately strong correlation with remission rates by the
4th visit, and a strong significant correlation was observable by the 5th visit. Overall relapse
rate showed a significant strong correlation with baseline HCL-32 3rd part score. Therefore our
results indicate that there is an association between baseline-assessed lifetime hypomania
scores and higher remission and lower relapse rates during 6-month lamotrigine treatment
indicating the efficacy of lamotrigine among patients with hypomania during their illness
course.
Keywords: lamotrigine, HCL-32, hypomania, remission, relapse<\/p>\n<\/div>\n
[\/et_pb_toggle][et_pb_blurb title=”The biological background of the comorbidity of depression and cancer” url=”https:\/\/mppt.hu\/magazin\/pdf\/xx-evfolyam-2-szam\/peter_honlapra.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_max_width=”105%” content_max_width=”1100px” _builder_version=”4.6.6″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/xx-evfolyam-2-szam\/peter_honlapra.pdf”]<\/p>\n
L\u00e1szl\u00f3 P\u00e9ter\u00a0<\/p>\n
[\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ _builder_version=”3.22.2″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px”]<\/p>\n
Depression is a common comorbid condition in patients with cancer, but the background
mechanisms underlying the relationship between depression and cancer are not well clarified.
Depression and cancer are prevalent public health problems in the Western world. In this
article, I review the recent knowledge regarding possible etiological mechanisms in particular
biological contexts. Inflammation and chronic stress play a role in the development of both
types of disease, which can explain high comorbidity. Depression in cancer patients increases
the time of hospitalization and mortality, lowers quality of life, decreases compliance, and
results in worse prognosis.
Keywords: depression, cancer, inflammation, chronic stress, mortality, comorbidity<\/p>\n<\/div>\n
[\/et_pb_toggle][et_pb_blurb title=”Hypocapnia and mental stress can trigger vicious circles in critically ill patients due to energy imbalance: a hypothesis presented through cardiogenic pulmonary oedema” url=”https:\/\/mppt.hu\/magazin\/pdf\/xx-evfolyam-2-szam\/sikter_honlapra.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_max_width=”105%” content_max_width=”1100px” _builder_version=”4.6.6″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/xx-evfolyam-2-szam\/sikter_honlapra.pdf”]<\/p>\n
Andras Sikter<\/p>\n
[\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ _builder_version=”3.22.2″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px”]<\/p>\n
Hypocapnia and mental stress can trigger vicious circles in critically ill patients due to energy imbalance: a hypothesis presented through cardiogenic pulmonary oedema <\/b><\/p>\n
A<\/b>NDRAS <\/b>S<\/b>IKTER <\/b><\/p>\n
Municipal Clinic of Szentendre, Internal Medicine, Szentendre, Hungary <\/span><\/i><\/p>\n The pathophysiologic significance of hypocapnia is strongly underestimated both in func- tional and organic diseases. Alterations of carbon dioxide levels immediately appear in the cytoplasm, causing abrupt pH changes. Compensatory mechanisms develop with latency, so intracellular alkalosis or acidosis can affect metabolism for hours\/days. Hyperventilation alkalosis increases metabolic energy\/O2 demand, while ATP production is often reduced due to developing hypophosphatemia. A healthy organism serves the increased energy demand conveniently, as a consequence, the excitability of the corticospinal and neuromuscular sys- tems grows. Functional diseases can occur due to increased membrane Ca<\/span>2<\/span>+ <\/span>transients but tissues remain structurally unchanged. By contrast, a critically ill myocardium cannot satisfy the increased energy demand caused by acute hypocapnia. Vicious circles can occur, with cardiac forward and backward failure; pulmonary wedge pressure increases parallel with the lack of energy which can lead to pulmonary oedema and death. Hypocapnia can generate fatal vicious circles in several critical illnesses. Sympathicotonia and hypocapnia enhance arousal and make biological systems energetically unstable, thus vicious circles almost una- voidably occur. Somatic and psychic processes mutually influence each other, resulting in psychosomatic or somatopsychic disorders. The ability to provide energy supplies can be an important dividing line between organic and functional diseases. <\/span>(Neuropsychopharmacol Hung 2018; 20(2): 65\u201374) <\/span><\/i><\/p>\n [\/et_pb_toggle][et_pb_blurb title=”Emotion regulation and heart rate variability” url=”https:\/\/mppt.hu\/magazin\/pdf\/xx-evfolyam-2-szam\/szemenyei_honlapra.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_max_width=”105%” content_max_width=”1100px” _builder_version=”4.6.6″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/xx-evfolyam-2-szam\/szemenyei_honlapra.pdf”]<\/p>\n Eszter Szemenyei , Nat\u00e1lia Kocsel , \u00c1gota \u00d6rk\u00e9nyi \u00e9s Gy\u00f6ngyi K\u00f6k\u00f6nyei <\/p>\n [\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ _builder_version=”3.22.2″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px”]<\/p>\n Heart rate variability (HRV) has been receiving increasing attention not just in medical but also the deficits of emotion regulation or disregulated emotional states can be important media- examining the connection of emotion regulation and resting and\/or phasic HRV. [\/et_pb_toggle][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/borito_honlapra_2018_06_kicsi.jpg” url_new_window=”on” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.6.5″ box_shadow_style=”preset3″][\/et_pb_image][\/et_pb_column][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Volume 20, Issue 2, June 2018 \u00a0Prof Dr. G\u00e1bor Faludi\u00a0T\u00e1rsas\u00e1gunk tiszt\u00faj\u00edt\u00f3 k\u00f6zgy\u0171l\u00e9s\u00e9t 2018. \u00e1prilis 23-\u00e1n tartottuk. Szomor\u00fa aktualit\u00e1s\u00e1t az adta, hogy tavaly j\u00faliusban meghalt Gaszner P\u00e9ter, aki 1980-t\u00f3l 37 \u00e9ven kereszt\u00fcl volt az \u00e1ltala alap\u00edtottPszichofarmakol\u00f3giai Egyes\u00fclet, jelenlegi nev\u00e9n Magyar Pszichofarmakol\u00f3gusok T\u00e1rsas\u00e1g\u00e1nak eln\u00f6ke. Eln\u00f6ks\u00e9ge alatt a T\u00e1rsas\u00e1g akt\u00edv szakmai k\u00f6z\u00e9leti tev\u00e9kenys\u00e9get fejtett ki, konferenci\u00e1kat szervezett,tudom\u00e1nyos szaklapot […]<\/p>\n","protected":false},"author":4,"featured_media":48286,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"project_category":[57],"project_tag":[],"class_list":["post-48520","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-neuropsychopharmacologia-hungarica-2-en"],"_links":{"self":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project\/48520","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/comments?post=48520"}],"version-history":[{"count":16,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project\/48520\/revisions"}],"predecessor-version":[{"id":49508,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project\/48520\/revisions\/49508"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/media\/48286"}],"wp:attachment":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/media?parent=48520"}],"wp:term":[{"taxonomy":"project_category","embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project_category?post=48520"},{"taxonomy":"project_tag","embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project_tag?post=48520"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
in psychological research. Several studies show that mental disorders are associated with lower
levels of HRV. Therefore, HRV has been considered as a transdiagnostic biomarker. The current
review spreads light on the possibility that in the connection of HRV and psychopathologies<\/p>\n
tors. Accordingly, we review the results of the questionnaire-based and experimental studies<\/p>\n
Keywords: heart rate variability, emotion regulation, tonic and phasic HRV, rumination, worry,
perseverative cognitions, mental health<\/p>\n<\/div>\n