{"id":49323,"date":"2013-03-27T08:10:00","date_gmt":"2013-03-27T08:10:00","guid":{"rendered":"https:\/\/mppt.hu\/project\/2013-marcius-xv-evfolyam-1-szam\/"},"modified":"2020-10-29T15:36:32","modified_gmt":"2020-10-29T15:36:32","slug":"2013-marcius-xv-evfolyam-1-szam","status":"publish","type":"project","link":"https:\/\/mppt.hu\/en\/project\/2013-marcius-xv-evfolyam-1-szam\/","title":{"rendered":"Volume 15, Issue 1, March 2013"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.22.7&#8243; custom_padding=&#8221;||5px|||&#8221;][et_pb_row _builder_version=&#8221;3.25&#8243;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;3.27.4&#8243;]<\/p>\n<h4 style=\"text-align: center;\">VOLUME 15, ISSUE 1, MARCH 2013<\/h4>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; _builder_version=&#8221;3.22.3&#8243; custom_padding=&#8221;24px|0px|25px|0px|false|false&#8221;][et_pb_column type=&#8221;3_4&#8243; specialty_columns=&#8221;3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_row_inner _builder_version=&#8221;3.25&#8243;][et_pb_column_inner saved_specialty_column_type=&#8221;3_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;Editoral in Hungarian &#8221; url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/szerklevel_kovacs.pdf&#8221; url_new_window=&#8221;on&#8221; image=&#8221;https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png&#8221; icon_placement=&#8221;left&#8221; image_max_width=&#8221;105%&#8221; content_max_width=&#8221;1100px&#8221; _builder_version=&#8221;3.22.7&#8243; header_font=&#8221;||||||||&#8221; header_font_size=&#8221;17px&#8221; header_line_height=&#8221;1.3em&#8221; body_font=&#8221;||on||||||&#8221; body_line_height=&#8221;1.3em&#8221; link_option_url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/szerklevel_kovacs.pdf&#8221; link_option_url_new_window=&#8221;on&#8221;]<\/p>\n<p>G\u00e1bor Kov\u00e1cs<\/p>\n<p>[\/et_pb_blurb][et_pb_toggle title=&#8221;Abstract&#8221; closed_toggle_text_color=&#8221;#000000&#8243; closed_toggle_background_color=&#8221;rgba(0,0,0,0)&#8221; icon_color=&#8221;#0c71c3&#8243; _builder_version=&#8221;4.6.6&#8243; title_font=&#8221;|600|||||||&#8221; title_letter_spacing=&#8221;1px&#8221; text_orientation=&#8221;justified&#8221; custom_padding=&#8221;0px||10px&#8221; border_width_all=&#8221;0px&#8221; border_width_bottom=&#8221;1px&#8221;]<\/p>\n<p class=\"art\"><span style=\"color: #666666; font-size: 14px;\">A klinikusok a gy\u00f3gyszeres ter\u00e1pia megv\u00e1laszt\u00e1sakor k\u00e9nytelenek figyelembe venni a finansz\u00edroz\u00f3 d\u00f6nt\u00e9s\u00e9t, azaz a leggyakrabban a j\u00f3l bev\u00e1lt origin\u00e1lis k\u00e9sz\u00edtm\u00e9ny helyett egy generikus szert \u00edrnak fel betegeiknek. Az ut\u00f3bbiak gy\u00e1rt\u00f3i eredm\u00e9nyes bioekvivalencia vizsg\u00e1lat ut\u00e1n gyakorlatilag egy\u00e9b szakmai felt\u00e9tel n\u00e9lk\u00fcl forgalomba hozhatj\u00e1k gy\u00f3gyszer\u00fcket, term\u00e9szetesen j\u00f3val olcs\u00f3bban, mint amennyibe az eredeti ker\u00fcl. Van olyan pszichofarmakon, amelynek p\u00e9ld\u00e1ul mintegy t\u00edz generikuma l\u00e9tezik, j\u00f3l ismert \u00e9s ismeretlen gy\u00e1rt\u00f3k \u00e1ltal el\u0151\u00e1ll\u00edtva. A finansz\u00edroz\u00e1si szab\u00e1lyokon bel\u00fcl a klinikus megpr\u00f3b\u00e1lja azt a k\u00e9sz\u00edtm\u00e9nyt kiv\u00e1lasztani, amelynek gy\u00e1rt\u00f3j\u00e1t megb\u00edzhat\u00f3nak tartja. El\u0151fordul azonban, hogy csal\u00f3dnia kell. Egy, a vil\u00e1gon szinte minden\u00fctt elismert gy\u00f3gyszergy\u00e1rt\u00f3 n\u00e9h\u00e1ny h\u00f3nappal ezel\u0151tt k\u00e9nytelen volt visszah\u00edvni az amerikai piacr\u00f3l generikusk\u00e9nt el\u0151\u00e1ll\u00edtott, k\u00e9sleltetett felsz\u00edv\u00f3d\u00e1s\u00fa bupropion k\u00e9sz\u00edtm\u00e9ny\u00e9t (1), mivel az origin\u00e1lis k\u00e9sz\u00edtm\u00e9nyr\u0151l \u00e1tv\u00e1lt\u00f3 betegek t\u00f6bb mint 50%-a relapszusba ker\u00fclt, depressz\u00edv t\u00fcnetei visszat\u00e9rtek. Az FDA, az amerikai gy\u00f3gyszer\u00e9szeti int\u00e9zet felsz\u00f3l\u00edtotta a gy\u00e1rt\u00f3t hat\u00e9konys\u00e1gi vizsg\u00e1lat elv\u00e9gz\u00e9s\u00e9re, amely azonban eredm\u00e9nytelen volt a kev\u00e9s beteg bevon\u00e1sa miatt. Ekkor a hivatal \u00e1ltala szponzor\u00e1lt bioekvivalencia vizsg\u00e1latot v\u00e9gzett, amelybe 24 eg\u00e9szs\u00e9ges egy\u00e9nt vontak be. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy a generikus k\u00e9sz\u00edtm\u00e9ny hat\u00e9kony vegy\u00fclet\u00e9b\u0151l az origin\u00e1lishoz viszony\u00edtva j\u00f3val kevesebb sz\u00edv\u00f3dott fel, a v\u00e9rben alacsony koncentr\u00e1ci\u00f3t lehetett kimutatni. Mindez magyar\u00e1zta a hat\u00e1s elmarad\u00e1s\u00e1t. Az FDA felsz\u00f3l\u00edtotta a gy\u00e1rt\u00f3t a gy\u00f3gyszer bevon\u00e1s\u00e1ra, ami meg is t\u00f6rt\u00e9nt. Igaz, a forgalomban l\u00e9v\u0151 tov\u00e1bbi n\u00e9gy generikummal nem t\u00f6rt\u00e9nt hasonl\u00f3 elj\u00e1r\u00e1s. . . .<\/span><\/p>\n<div class=\"artbody\"><\/div>\n<p>[\/et_pb_toggle][et_pb_blurb title=&#8221;Automated Neuropsychological Test Battery in depression \u2013 preliminary data&#8221; url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/egerhazi.pdf&#8221; url_new_window=&#8221;on&#8221; image=&#8221;https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png&#8221; icon_placement=&#8221;left&#8221; image_max_width=&#8221;105%&#8221; content_max_width=&#8221;1100px&#8221; _builder_version=&#8221;3.22.7&#8243; header_font=&#8221;||||||||&#8221; header_font_size=&#8221;17px&#8221; header_line_height=&#8221;1.3em&#8221; body_font=&#8221;||on||||||&#8221; body_line_height=&#8221;1.3em&#8221; link_option_url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/egerhazi.pdf&#8221; link_option_url_new_window=&#8221;on&#8221;]<\/p>\n<p>Anik\u00f3 \u00c9gerh\u00e1zi, Petra Balla, Andrea Ritzl, Zs\u00f3fia Varga, Ede\u00a0 Frecska and Roland Berecz<\/p>\n<p>[\/et_pb_blurb][et_pb_toggle title=&#8221;Abstract&#8221; closed_toggle_text_color=&#8221;#000000&#8243; closed_toggle_background_color=&#8221;rgba(0,0,0,0)&#8221; icon_color=&#8221;#0c71c3&#8243; _builder_version=&#8221;3.22.7&#8243; title_font=&#8221;|600|||||||&#8221; title_letter_spacing=&#8221;1px&#8221; text_orientation=&#8221;justified&#8221; custom_padding=&#8221;0px||10px&#8221; border_width_all=&#8221;0px&#8221; border_width_bottom=&#8221;1px&#8221;]<\/p>\n<p class=\"art\">Aims: Studies have demonstrated neuropsychological deficits across a variety of cognitive<br \/>domains in patients with major depressive disorder (MDD) during acute episode. However,<br \/>limited data are available concerning whether these abnormalities persist in the remission<br \/>phase. Methods: In the present study CANTAB (Cambridge Automated Neuropsychological<br \/>Test Battery) was used to evaluate the cognitive impairment associated with depression during<br \/>acute episode and in remission. 25 patients with MDD during an acute episode and 11 patients<br \/>also during remission were tested with CANTAB. Results: During the acute episode,<br \/>Delayed matching to sample, Paired associate learning, Spatial recognition memory, Rapid visual<br \/>processing and Visuospatial planning were impaired. In remission the improvement of visual<br \/>learning ability, spatial recognition memory, psychomotor speed, and executive function was<br \/>observed. Conclusions: The results suggest that MDD is associated with neurocognitive dysfunctions in different domains, the most prominent deficit was found in the Paired associate<br \/>learning test, which requires both the elaboration of \u201dfrontal strategies\u201d and the \u201dmnemonic<br \/>processes\u201d. Cognitive impairment was found to improve partly in remission, suggesting that<br \/>an individual\u2019s current mood interacts with the ability to perform a cognitive task. Besides<br \/>these state markers, trait deficits are important because cognitive impairments which do not<br \/>improve in remission might serve as endophenotypes of depression.<\/p>\n<p class=\"art\"><em>(Neuropsychopharmacol Hung 2013; 15(1): 5-11)<\/em><\/p>\n<p class=\"art\">Keywords: cognitive function, unipolar depression, remission, endophenotypes<\/p>\n<p>[\/et_pb_toggle][et_pb_blurb title=&#8221;New data for the pathomechanism of neuropathic pain: therapeutic evidences&#8221; url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/tajti.pdf&#8221; url_new_window=&#8221;on&#8221; image=&#8221;https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png&#8221; icon_placement=&#8221;left&#8221; image_max_width=&#8221;105%&#8221; content_max_width=&#8221;1100px&#8221; _builder_version=&#8221;3.22.7&#8243; header_font=&#8221;||||||||&#8221; header_font_size=&#8221;17px&#8221; header_line_height=&#8221;1.3em&#8221; body_font=&#8221;||on||||||&#8221; body_line_height=&#8221;1.3em&#8221; link_option_url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/tajti.pdf&#8221; link_option_url_new_window=&#8221;on&#8221;]<\/p>\n<p>J\u00e1nos Tajti, D\u00e9lia\u00a0 Szok and L\u00e1szl\u00f3 V\u00e9csei<\/p>\n<p>[\/et_pb_blurb][et_pb_toggle title=&#8221;Abstract&#8221; closed_toggle_text_color=&#8221;#000000&#8243; closed_toggle_background_color=&#8221;rgba(0,0,0,0)&#8221; icon_color=&#8221;#0c71c3&#8243; _builder_version=&#8221;4.6.6&#8243; title_font=&#8221;|600|||||||&#8221; title_letter_spacing=&#8221;1px&#8221; text_orientation=&#8221;justified&#8221; custom_padding=&#8221;0px||10px&#8221; border_width_all=&#8221;0px&#8221; border_width_bottom=&#8221;1px&#8221;]<\/p>\n<p class=\"art\"><span style=\"color: #666666; font-size: 14px;\">The present work is based on literature data from PubMed. Neuropathic pain is caused by<br \/> a lesion or disease of the somatosensory system. Peripheral and central sensitization play<br \/> a crucial role in its pathomechanism. The clinical symptoms are mainly characterized by<br \/> burning and throbbing pain and sensory disturbances like hyperalgesia and allodynia.<br \/> Therapeutic recommendations are antidepressants, antiepileptics, opioids and neuro-stimulation methods.<\/span><\/p>\n<p class=\"art\"><span style=\"color: #666666; font-size: 14px;\"><\/span><\/p>\n<div class=\"artbody\">\n<p><em>(Neuropsychopharmacol Hung 2013; 15(1): 13-17)<\/em><\/p>\n<p>Keywords: neuropathic pain, peripheral sensitization, central sensitization, therapeutic evidences<\/p>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_blurb title=&#8221;Pulvinar&#8221; url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/szirmai.pdf&#8221; url_new_window=&#8221;on&#8221; image=&#8221;https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png&#8221; icon_placement=&#8221;left&#8221; image_max_width=&#8221;105%&#8221; content_max_width=&#8221;1100px&#8221; _builder_version=&#8221;3.22.7&#8243; header_font=&#8221;||||||||&#8221; header_font_size=&#8221;17px&#8221; header_line_height=&#8221;1.3em&#8221; body_font=&#8221;||on||||||&#8221; body_line_height=&#8221;1.3em&#8221; link_option_url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/szirmai.pdf&#8221; link_option_url_new_window=&#8221;on&#8221;]<\/p>\n<p>Imre Szirmai<\/p>\n<p>[\/et_pb_blurb][et_pb_toggle title=&#8221;Abstract&#8221; closed_toggle_text_color=&#8221;#000000&#8243; closed_toggle_background_color=&#8221;rgba(0,0,0,0)&#8221; icon_color=&#8221;#0c71c3&#8243; _builder_version=&#8221;4.6.6&#8243; title_font=&#8221;|600|||||||&#8221; title_letter_spacing=&#8221;1px&#8221; text_orientation=&#8221;justified&#8221; custom_padding=&#8221;0px||10px&#8221; border_width_all=&#8221;0px&#8221; border_width_bottom=&#8221;1px&#8221;]<\/p>\n<p class=\"art\"><span style=\"color: #666666; font-size: 14px;\">The pulvinar is the largest nucleus of the thalamus. Its lateral and inferior areas have rich<br \/> connections with the visual- and dorsolateral parietal cortices. Several cells in the medial<br \/> and upper area connect the anterior cingulum and the premotor and prefrontal association<br \/> areas. This neuronal network was considered to organize the saccades and visual attention.<br \/> Other cells in the medial nucleus have axonal connections with paralimbic-, insular and higher<br \/> order association-cortices. The medial structure integrates complex sensory information with<br \/> limbic reactivity settings, transmitting these to the temporal and parieto-occipital centres.<br \/> The pulvinar is supplied by the posterior chorioideal artery. Visual salience is considered to be<br \/> an important function of the pulvinar. Visual selection enables subjects to choose the actually<br \/> adequate behavioral act. To serve the visual salience the pulvinar may also inhibit inapproriate<br \/> eye movements. The pulvinar appears to be a key structure of the EEG\u2019s alpha rhythm generator, acting together with the parietooccipital and temporal cortices. Dynamic fluctuation of<br \/> BOLD signals on fMRI correlates well with the change of alpha power even in resting state.<br \/> We presume that the pulvinar is part of a closed cortico-subcortical circuit, analogous with<br \/> the striatum, but the output of the pulvinar initiates complex behavioral reactions, including<br \/> perception, selective attention and emotions. Damage of the pulvinar may elicit contralateral<br \/> visual neglect, because of the dissociation of the neuronal network integrated by the superior<br \/> temporal area. Increased activity of the pulvinar was found during abrupt reaction to fearful<br \/> visual signals; and also in the etiopathology of endogenous depressions through the alteration of serotonin transporters. Increased bilateral signal intensity of the pulvinar on MRI was<br \/> detected in cases of the new variants of Creutzfeldt-Jakob- and Fabry diseases.\u00a0\u00a0<\/span><\/p>\n<p class=\"art\"><span style=\"color: #666666; font-size: 14px;\"><\/span><\/p>\n<div class=\"artbody\">\n<p><em>(Neuropsychopharmacol Hung 2013; 15(1): 19-26)<\/em><\/p>\n<p>Keywords: pulvinar, neural net, visual space, alpha generator<\/p>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_blurb title=&#8221;The possibilities of suicide prevention in adolescents. A holistic approach to protective and risk factors&#8221; url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/kalmar.pdf&#8221; url_new_window=&#8221;on&#8221; image=&#8221;https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png&#8221; icon_placement=&#8221;left&#8221; image_max_width=&#8221;105%&#8221; content_max_width=&#8221;1100px&#8221; _builder_version=&#8221;3.22.7&#8243; header_font=&#8221;||||||||&#8221; header_font_size=&#8221;17px&#8221; header_line_height=&#8221;1.3em&#8221; body_font=&#8221;||on||||||&#8221; body_line_height=&#8221;1.3em&#8221; link_option_url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/kalmar.pdf&#8221; link_option_url_new_window=&#8221;on&#8221;]<\/p>\n<p>S\u00e1ndor Kalm\u00e1r<\/p>\n<p>[\/et_pb_blurb][et_pb_toggle title=&#8221;Abstract&#8221; closed_toggle_text_color=&#8221;#000000&#8243; closed_toggle_background_color=&#8221;rgba(0,0,0,0)&#8221; icon_color=&#8221;#0c71c3&#8243; _builder_version=&#8221;3.22.7&#8243; title_font=&#8221;|600|||||||&#8221; title_letter_spacing=&#8221;1px&#8221; text_orientation=&#8221;justified&#8221; custom_padding=&#8221;0px||10px&#8221; border_width_all=&#8221;0px&#8221; border_width_bottom=&#8221;1px&#8221;]<\/p>\n<p class=\"art\">There is no other such complex physical, biological, somatic, mental, psychological, psychiatric, cultural, social and spiritual phenomenon and general public health problem, so much<br \/>unexplained, meaningless, so tragic, painful, and unreasonable, so difficult, contradictory and<br \/>mystified like suicide. In spite of the several already identified background factors, we do not<br \/>and we can not know the real reasons behind suicide, because suicide is multi-causal, and can<br \/>never be traced back to one single cause, but there are always many biological, psychologicalpsychiatric, historical, social and cultural factors involved in its development. However, the<br \/>strongest suicide risk factor is an unrecognized and untreated mental disorder. Suicide among<br \/>young people is one of the most serious public health problems. In Hungary 1395 young<br \/>people lost their lives due to suicide in the 24&gt; age group between 2000-2010, 1150 males and<br \/>245 females. According to epidemiological studies, 24.7% of children and adolescents suffer<br \/>from some form of behaviour-, conduct- or other psychiatric disorders. Among adolescents<br \/>(aged 15-24) suicide was the first leading cause of death in 2010. Despite great advances in<br \/>the psychopharmacology and psychotherapy of mental disorders, suicides persist as a major<br \/>cause of mortality, especially among the 15-24-year old population. Victims of suicide are not<br \/>healthy individuals. They always suffer from psychiatric or mental, physical or somatic, cultural<br \/>(social, historical, mythological) and spiritual disorders. The author tries to classify suicide protective and risk factors according to physical-biological, mental-psychological, cultural-social,<br \/>and spiritual aspects. However, it must be remembered that these factors are not necessarily<br \/>present in each and every case and may vary from one country to another, one person to<br \/>another, depending on cultural, political, (spiritual) and economical features. Risk and protective factors can occur (1) at the physical or biological-somatic level which includes physical<br \/>circumstances, genetics, health, and diseases; (2) at the mental or psychological level, which<br \/>includes mental health, self-esteem, and ability to deal with difficult circumstances, manage<br \/>emotions, or cope with stress; (3) at the cultural level or the broader life environment, and this<br \/>includes social, political, environmental, and economic factors that contribute to available<br \/>options and quality of life; (4) at the social level, which includes relationships and involvement<br \/>with others such as family, friends, workmates, the wider community and the person\u2019s sense<br \/>of belonging; (5) at the spiritual level, which includes faith, hope, charity, despair, salvation.<br \/>Children and adolescents spend a lot of time at school, so teachers must be educated to<br \/>notice any warning signs of suicide, but the majority of pedagogues not only do not know<br \/>the most important mental and psychosomatic symptoms, but do not recognize them in<br \/>children and do not know how to handle them either. Hopelessness is the most important<br \/>spiritual risk factor. The Beck Hopelessness Scale is a tool for easy application in general practice.<br \/>The author lists some important symptoms and signs that neither parents nor teachers are<br \/>able to recognize and handle, and provides useful advice for prevention.<\/p>\n<p class=\"art\"><em>(Neuropsychopharmacol Hung 2013; 15(1): 27-39)<\/em><\/p>\n<p class=\"art\">Keywords: suicide, adolescents, prevention, risk and protective factors, hopelessness,<br \/>spirituality, holistic approach<\/p>\n<p>[\/et_pb_toggle][et_pb_blurb title=&#8221;Affective disorders and their treatment during pregnancy and after birth \u2013 a review&#8221; url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/felegyhazy.pdf&#8221; url_new_window=&#8221;on&#8221; image=&#8221;https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png&#8221; icon_placement=&#8221;left&#8221; image_max_width=&#8221;105%&#8221; content_max_width=&#8221;1100px&#8221; _builder_version=&#8221;3.22.7&#8243; header_font=&#8221;||||||||&#8221; header_font_size=&#8221;17px&#8221; header_line_height=&#8221;1.3em&#8221; body_font=&#8221;||on||||||&#8221; body_line_height=&#8221;1.3em&#8221; link_option_url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/felegyhazy.pdf&#8221; link_option_url_new_window=&#8221;on&#8221;]<\/p>\n<p>Zsolt\u00a0 F\u00e9legyh\u00e1zy and Adler Mats<\/p>\n<p>[\/et_pb_blurb][et_pb_toggle title=&#8221;Abstract&#8221; closed_toggle_text_color=&#8221;#000000&#8243; closed_toggle_background_color=&#8221;rgba(0,0,0,0)&#8221; icon_color=&#8221;#0c71c3&#8243; _builder_version=&#8221;4.6.6&#8243; title_font=&#8221;|600|||||||&#8221; title_letter_spacing=&#8221;1px&#8221; text_orientation=&#8221;justified&#8221; custom_padding=&#8221;0px||10px&#8221; border_width_all=&#8221;0px&#8221; border_width_bottom=&#8221;1px&#8221;]<\/p>\n<p class=\"art\">Treatment and management of affective disorders associated with pregnancy is still an underemphasized field receiving little attention, furthermore, it is burdened with misinformation<br \/> as well as incomplete or missing knowledge. Professionals of related fields (psychiatrists,<br \/> obstetrician-gynecologists) often provide patients with contradicting information or, due to<br \/> their lack of sufficient knowledge, keep referring the patient for information between different<br \/> services. However, there is an increasing amount of data and information available, suitable<br \/> for drawing conclusions and making it possible to provide adequate and credible counselling<br \/> and information for pregnant women or family planning couples. In the present paper we aim<br \/> to facilitate this process by reviewing the currently available information.<\/p>\n<p class=\"art\"><em style=\"color: #666666; font-size: 14px;\">(Neuropsychopharmacol Hung 2013; 15(1): 40-48)<\/em><\/p>\n<p class=\"art\"><em style=\"color: #666666; font-size: 14px;\"><\/em><\/p>\n<div class=\"artbody\">\n<p>Keywords: affective disorders, pregnancy, lactation, antidepressants, mood stabilisers, antipsychotics, birth defects<\/p>\n<\/div>\n<p>[\/et_pb_toggle][et_pb_blurb title=&#8221;Extended release quetiapine fumarate and pregnancy&#8221; url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/tenyi.pdf&#8221; url_new_window=&#8221;on&#8221; image=&#8221;https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png&#8221; icon_placement=&#8221;left&#8221; image_max_width=&#8221;105%&#8221; content_max_width=&#8221;1100px&#8221; _builder_version=&#8221;3.22.7&#8243; header_font=&#8221;||||||||&#8221; header_font_size=&#8221;17px&#8221; header_line_height=&#8221;1.3em&#8221; body_font=&#8221;||on||||||&#8221; body_line_height=&#8221;1.3em&#8221; link_option_url=&#8221;https:\/\/mppt.hu\/magazin\/pdf\/xv-evfolyam-1-szam\/tenyi.pdf&#8221; link_option_url_new_window=&#8221;on&#8221;]<\/p>\n<p>Tam\u00e1s T\u00e9nyi, \u00c1gnes Nagy, R\u00f3bert\u00a0 Herold and S\u00e1ndor Fekete<\/p>\n<p>[\/et_pb_blurb][et_pb_toggle title=&#8221;Abstract&#8221; closed_toggle_text_color=&#8221;#000000&#8243; closed_toggle_background_color=&#8221;rgba(0,0,0,0)&#8221; icon_color=&#8221;#0c71c3&#8243; _builder_version=&#8221;3.22.7&#8243; title_font=&#8221;|600|||||||&#8221; title_letter_spacing=&#8221;1px&#8221; text_orientation=&#8221;justified&#8221; custom_padding=&#8221;0px||10px&#8221; border_width_all=&#8221;0px&#8221; border_width_bottom=&#8221;1px&#8221;]<\/p>\n<p class=\"art\">We report on a case of a patient with schizophrenia who was taking 700 mg extended release<br \/>quetiapine fumarate during her entire pregnancy to prevent relapse. At week 41 she gave<br \/>birth to a healthy boy. The newborn\u2019s weight was 3410 gramms, his height was 49 cm, his<br \/>Apgar score in the first minute was 9, and at 5 minutes, it was 10.<\/p>\n<p class=\"art\"><em>(Neuropsychopharmacol Hung 2013; 15(1): 49-50)<\/em><\/p>\n<p class=\"art\">Keywords: extended release quetiapine fumarate, pregnancy, schizophrenia<\/p>\n<p>[\/et_pb_toggle][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/mppt.hu\/wp-content\/uploads\/2019\/05\/cimlap_2013_marcius_kicsi.jpg&#8221; align_tablet=&#8221;center&#8221; align_phone=&#8221;&#8221; align_last_edited=&#8221;on|desktop&#8221; _builder_version=&#8221;3.23&#8243; box_shadow_style=&#8221;preset3&#8243;][\/et_pb_image][\/et_pb_column][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>VOLUME 15, ISSUE 1, MARCH 2013G\u00e1bor Kov\u00e1csA klinikusok a gy\u00f3gyszeres ter\u00e1pia megv\u00e1laszt\u00e1sakor k\u00e9nytelenek figyelembe venni a finansz\u00edroz\u00f3 d\u00f6nt\u00e9s\u00e9t, azaz a leggyakrabban a j\u00f3l bev\u00e1lt origin\u00e1lis k\u00e9sz\u00edtm\u00e9ny helyett egy generikus szert \u00edrnak fel betegeiknek. Az ut\u00f3bbiak gy\u00e1rt\u00f3i eredm\u00e9nyes bioekvivalencia vizsg\u00e1lat ut\u00e1n gyakorlatilag egy\u00e9b szakmai felt\u00e9tel n\u00e9lk\u00fcl forgalomba hozhatj\u00e1k gy\u00f3gyszer\u00fcket, term\u00e9szetesen j\u00f3val olcs\u00f3bban, mint amennyibe az eredeti [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":48312,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"project_category":[62],"project_tag":[],"class_list":["post-49323","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-2013-en"],"_links":{"self":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project\/49323","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/comments?post=49323"}],"version-history":[{"count":8,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project\/49323\/revisions"}],"predecessor-version":[{"id":49688,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project\/49323\/revisions\/49688"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/media\/48312"}],"wp:attachment":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/media?parent=49323"}],"wp:term":[{"taxonomy":"project_category","embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project_category?post=49323"},{"taxonomy":"project_tag","embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project_tag?post=49323"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}