[et_pb_section fb_built=”1″ _builder_version=”3.22.7″ custom_padding=”||5px|||”][et_pb_row _builder_version=”3.25″][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.6.6″]<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ specialty=”on” _builder_version=”3.22.3″ custom_padding=”24px|0px|25px|0px|false|false”][et_pb_column type=”3_4″ specialty_columns=”3″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_row_inner _builder_version=”3.25″][et_pb_column_inner saved_specialty_column_type=”3_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_blurb title=”Editoral in hungarian” url=”https:\/\/mppt.hu\/magazin\/pdf\/xi-evfevfolyam-3-szam\/kognitiv-funkciok-vizsgalata-alkoholfuegg-betegeknel.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_max_width=”105%” content_max_width=”1100px” _builder_version=”4.6.6″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” custom_padding=”14px|||||” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/xi-evfevfolyam-3-szam\/kognitiv-funkciok-vizsgalata-alkoholfuegg-betegeknel.pdf” link_option_url_new_window=”on”]<\/p>\n
R\u00e9ka Mlinarics, Oguz Kelemen, Tam\u00e1s\u00a0<\/sup>Sefcsik, Dezs\u0151\u00a0<\/sup>N\u00e9meth<\/p>\n [\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ _builder_version=”3.23.3″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px”]<\/p>\n <\/p>\n<\/div>\n Az alkoholfu\u0308gg\u00f5s\u00e9g klinikai k\u00e9p\u00e9nek h\u00e1tter\u00e9ben jellegzetes kognit\u00edv inform\u00e1ci\u00f3feldolgoz\u00e1si folyamatok felt\u00e9telezhet\u00f5k. Kutat\u00e1sunkban ezek vizsg\u00e1lat\u00e1ra a gyakorlatban \u00e9s a klinikumban egyar\u00e1nt hat\u00e9konyan alkalmazott neuropszichol\u00f3giai teszteket haszn\u00e1ltuk. Avizsg\u00e1latban 20 legal\u00e1bb 6 h\u00f3napja absztinens, de a DSM-IV szerint diagnosztiz\u00e1lt alkoholfu\u0308gg\u00f5 beteg \u00e9s 20 illesztett kontroll szem\u00e9ly vett r\u00e9szt. A neuropszichol\u00f3giai deficitek m\u00e9r\u00e9s\u00e9re a komplex munkamem\u00f3ria ter\u00e9n a hall\u00e1si mondatterjedelem tesztet \u00e9s a ford\u00edtott sz\u00e1mterjedelem tesztet, a v\u00e9grehajt\u00f3 funkci\u00f3k ter\u00e9n a Trail Making A, Trail Making B, bet\u00fbfluencia, szemantikus fluencia tesztet, a verb\u00e1lis r\u00f6vidt\u00e1v\u00fa eml\u00e9kezet m\u00e9r\u00e9s\u00e9re a sz\u00e1mterjedelem \u00e9s a sz\u00f3lista visszamond\u00e1s tesztet, figyelmi tesztk\u00e9nt a Digit Symbol Substitution Tesztet alkalmaztuk. \u00c1ltal\u00e1nosabb mem\u00f3ria tesztk\u00e9nt a Rivermead Viselked\u00e9ses Mem\u00f3ria Tesztet haszn\u00e1ltuk. Eredm\u00e9nyek. A hossz\u00fa absztinenci\u00e1t tartani tud\u00f3 alkoholbetegekn\u00e9l a kognit\u00edv k\u00e9pess\u00e9gek k\u00e1rosod\u00e1sa megfigyelhet\u00f5 volt a v\u00e9grehajt\u00f3-funkci\u00f3t, a front\u00e1lis \u00e9s frontotempor\u00e1lis m\u00fbk\u00f6d\u00e9st vizsg\u00e1l\u00f3 tesztekn\u00e9l (cs\u00f6kkent szemantikus fluencia, hall\u00e1si mondatterjedelem \u00e9rt\u00e9kek). A vizsg\u00e1latban \u00e9rintettnek mutatkozott a kognit\u00edv feldolgoz\u00e1si sebess\u00e9g, illetve a pszichomotoros gyorsas\u00e1g ter\u00e9n is deficit volt \u00e9szlelhet\u00f5. Ugyanakkor a v\u00e9grehajt\u00f3 funkci\u00f3kat \u00e9s a szemantikus fluenci\u00e1t m\u00e9r\u00f5 tesztekben m\u00e9rt k\u00e1rosod\u00e1s az absztinencia id\u00f5tartalm\u00e1val ford\u00edtottan korrel\u00e1lt. Mindezek mellett az epizodikus, valamint a k\u00e9sleltetett mem\u00f3ria funkci\u00f3k, a Rivermead Viselked\u00e9ses Mem\u00f3ria Teszt eredm\u00e9nye nem mutatott szignifik\u00e1ns cs\u00f6kken\u00e9st, mely felvetheti a hossz\u00fat\u00e1v\u00fa mem\u00f3ria rekonszolid\u00e1ci\u00f3s lehet\u00f5s\u00e9g\u00e9t. A kognit\u00edv funkci\u00f3k, ezen belu\u0308l is a v\u00e9grehajt\u00f3 funkci\u00f3k, a szemantikus fluencia \u00e9rt\u00e9kek tekintet\u00e9ben javul\u00e1s volt kimutathat\u00f3, az absztinencia tart\u00e1s hossz\u00e1val ar\u00e1nyosan. Ugyanakkor sz\u00e1mos teru\u0308leten hossz\u00fat\u00e1v\u00fa absztinencia mellett is \u00e9szlelhet\u00f5 kognit\u00edv \u00e9rintetts\u00e9g, amely vagy primer \u00e9rintetts\u00e9gre utalhat, vagy az adott teru\u0308let sokkal lass\u00fabb regener\u00e1ci\u00f3j\u00e1rt jelezheti.<\/p>\n Kulcsszavak:<\/strong>\u00a0alkoholdependencia, alkohol, kognit\u00edv funkci\u00f3k, mem\u00f3ria, absztinencia<\/p>\n<\/div>\n [\/et_pb_toggle][et_pb_blurb title=”Why do hungarian men die early?” url=”https:\/\/mppt.hu\/magazin\/pdf\/xi-evfevfolyam-3-szam\/miert-halnak-meg-id-eltt-a.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_max_width=”105%” content_max_width=”1100px” _builder_version=”4.6.6″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” custom_margin=”52px|||||” custom_padding=”1px|||||” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/xi-evfevfolyam-3-szam\/miert-halnak-meg-id-eltt-a.pdf” link_option_url_new_window=”on”]<\/p>\n M\u00e1ria Kopp, \u00c1rp\u00e1d Skrabski<\/p>\n [\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ _builder_version=”4.6.6″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px”]<\/p>\n The mortality rate for 40-69 years old men was 12.2 \/thousand males of corresponding age in 1960 and 16.2 in 2005: it increased by 33 %, while among 40-69 years old women it decreased from 9.6 0\/thousand females of corresponding age to 7.8. The aim of the present follow up study was to analyze which psychosocial risk factors might explain the high premature mortality rates among Hungarian men? Participants in the Hungarostudy 2002 study, a nationally representative sample, 1130 men and 1529 women were contacted again in the follow up study in 2006, who in 2002 were between the age of 40-69 years. By 2006, 99 men (8.8%) and 53 women (3.5 %) died in this age group. Socioeconomic, psychosocial and work related measures, self-rated health, chronic disorders, depressive symptoms (BDI), WHO well-being, negative affect, self-efficacy, meaning in life and health behavioral factors were included in the analysis. After adjustment according to smoking, alcohol abuse, BMI, education and age a number of variables were significant predictors of mortality only in men: low education, low subjective\u00a0 \u00a0social status, low personal and family income, insecurity of work, no control in work, severe depression, no meaning in life, low social support from spouse, low social support from child. Socioeconomic and work related risk factors predicted KEYWORDS<\/strong>: premature mortality, gender differences, depression, chronic stress, psychosocial determinants<\/p>\n [\/et_pb_toggle][et_pb_blurb title=”Child-adolescent psychiatry to adult psychiatry: can we find those disorders in the adulthood which are tipically diagnosed in the childhood?” url=”https:\/\/mppt.hu\/magazin\/pdf\/xi-evfevfolyam-3-szam\/gyermekpszichiatria-a-felntt-pszichiatrianak-hova-lesznek.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_max_width=”105%” content_max_width=”1100px” _builder_version=”4.6.6″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” custom_padding=”15px|||||” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/xi-evfevfolyam-3-szam\/gyermekpszichiatria-a-felntt-pszichiatrianak-hova-lesznek.pdf” link_option_url_new_window=”on”]<\/p>\n Judit Bal\u00e1zs, J\u00falia G\u00e1doros, Csilla Prekop<\/p>\n [\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ _builder_version=”4.6.6″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px”]<\/p>\n The aim of the current manuscript is to provide a short overview on autisms, attention deficit hyperactivity disorder (ADHD) and Tourette syndrome. According to international data, the prevalence of autisms is 2-5\/10000 and the symptoms persistence during the entire life; the prevalence of ADHD among children and adolescents is 2,4-12,0% and the symptoms cause problem in 30-50% in the adulthood as well; while the prevalence of tic disorder is 1-6,6% among children and adolescents and the symptoms persistence in 10% in adulthood. According to Hungarian data, these disorders are relatively rare in adult psychiatric practice. Presenting case reports of adults with autisms, ADHD and Tourette syndrome, we would like to demonstrate the symptoms, treatment possibilities of these disorders and how they can influence the patients\u2019 quality of life.\u00a0<\/p>\n KEYWORDS<\/strong>: autism, attention deficit hyperactivity disorder (ADHD) and Tourette syndrome<\/p>\n [\/et_pb_toggle][et_pb_blurb title=”The role of carbon dioxide (and intracellular ph) in the pathomechanism of several mental disorders are the diseases of civilization caused by learnt behaviour, not the stress itself?” url=”https:\/\/mppt.hu\/magazin\/pdf\/xi-evfevfolyam-3-szam\/a-szendioxid-es-az-intracellularis-ph.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_max_width=”105%” content_max_width=”1100px” _builder_version=”4.6.6″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/xi-evfevfolyam-3-szam\/a-szendioxid-es-az-intracellularis-ph.pdf” link_option_url_new_window=”on”]<\/p>\n Andras Sikter, Gabor Faludi, Zoltan Rihmer<\/p>\n [\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ _builder_version=”3.23.3″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px”]<\/p>\n <\/p>\n<\/div>\n Are the diseases of civilization caused by learnt behaviour, not the stress itself?<\/em><\/p>\n The role of carbon dioxide (CO2<\/sub>) is underestimated in the pathomechanism of neuropsychiatric disorders, though it is an important link between psyche and corpus. The actual spiritual status also influences respiration (we start breathing rarely, frequently, irregularly, etc.) causing pH alteration in the organism; on the other hand the actual cytosolic pH of neurons is one of the main modifiers of Ca2+<\/sup>-conductance, hence breathing directly, quickly, and effectively influences the second messenger system through Ca2+<\/sup>-currents. (Decreasing pCO2<\/sub>\u00a0turns pH into alkalic direction, augments psychic arousal, while increasing pCO2<\/sub>\u00a0turns pH acidic, diminishes arousal.) One of the most important homeostatic function is to maintain or restore the permanence of H+<\/sup>-concentration, hence the alteration of CO2<\/sub>\u00a0level starts cascades of contraregulation. However it can be proved that there is no perfect compensation, therefore compensational mechanisms may generate psychosomatic disorders causing secondary alterations in the \u201cmilieu interieur\u201d. Authors discuss the special physico-chemical features of CO2<\/sub>, the laws of interweaving alterations of pCO2<\/sub>\u00a0and catecholamine levels (their feedback mechanism), the role of acute and chronic hypocapnia in several hyperarousal disorders (delirium, panic disorder, hyperventilation syndrome, generalized anxiety disorder, bipolar disorder), the role of \u201clocus minoris resistentiae\u201d in the pathomechanism of psychosomatic disorders. It is supposed that the diseases of civilization are caused not by the stress itself but the lack of human instinctive reaction to it, and this would cause long-lasting CO2<\/sub>\u00a0alteration. Increased brain-pCO2<\/sub>, acidic cytosol pH and\/or increased basal cytosolic Ca2+<\/sup>\u00a0level diminish inward Ca2+<\/sup>-current into cytosol, decrease arousal \u2013 they may cause dysthymia or depression. This state usually co-exists with ATP-deficiency and decreased cytosolic Mg2+<\/sup>\u00a0content. This energeticaland ion-constellation is also typical of ageingassociated and chronic organic disorders. It is the most important link between depression and organic disorders (e.g. coronary heart disease). The above-mentioned model is supported by the fact that H+<\/sup>\u00a0and\/or Ca2+<\/sup>\u00a0metabolism is affected by several drugs (catecholemines, serotonin, lithium, triaecetyluridine, thyroxine) and sleep deprivation, they act for the logically right direction.<\/p>\n KEYWORDS:<\/strong>\u00a0arousal, behaviour, bipolar disorder, carbon dioxide, delirium, depression, diseases of civilization, [\/et_pb_toggle][et_pb_blurb title=”Olanzapine pamoate: a stick in time? a review of the efficacy and safety profile of a new depot formulation of a secondgeneration antipsychotic” url=”https:\/\/mppt.hu\/magazin\/pdf\/xi-evfevfolyam-3-szam\/olanzapin-egy-szuras-jo-idbne-egy.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_max_width=”105%” content_max_width=”1100px” _builder_version=”4.6.6″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/xi-evfevfolyam-3-szam\/olanzapin-egy-szuras-jo-idbne-egy.pdf” link_option_url_new_window=”on”]<\/p>\n L. Citrome<\/p>\n [\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ _builder_version=”3.23.3″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px”]<\/p>\n Olanzapine pamoate, a long-acting depot preparation of olanzapine, is being evaluated by regulatory agencies for the treatment of schizophrenia. Clinical trial information was accessed by KEYWORDS<\/strong>: olanzapine, depot, long-acting, pamoate<\/p>\n [\/et_pb_toggle][et_pb_blurb title=”In waves\u2019 parlance: serotonin and sleep oscillations” url=”https:\/\/mppt.hu\/magazin\/pdf\/xi-evfevfolyam-3-szam\/hullamok-nyelven-a-szerotonin-es-az.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_max_width=”105%” content_max_width=”1100px” _builder_version=”4.6.6″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/xi-evfevfolyam-3-szam\/hullamok-nyelven-a-szerotonin-es-az.pdf” link_option_url_new_window=”on”]<\/p>\n R\u00f3bert B\u00f3dizs<\/p>\n [\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ _builder_version=”3.23.3″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px”]<\/p>\n The close and complex relationship between serotonin and sleep-waking states has special theoretical and practical importance. There are available scientific data regarding this issue, but the KEYWORDS<\/strong>: 5-HT2A receptor, sleep stages, [\/et_pb_toggle][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/mppt.hu\/wp-content\/uploads\/2020\/12\/2009_szeptember_small-e1608026821712.jpg” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.6.6″ hover_enabled=”0″ box_shadow_style=”preset3″ title_text=”2009_szeptember_small” sticky_enabled=”0″][\/et_pb_image][\/et_pb_column][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Volume 11, Issue 3, September 2009R\u00e9ka Mlinarics, Oguz Kelemen, Tam\u00e1s\u00a0Sefcsik, Dezs\u0151\u00a0N\u00e9meth Az alkoholfu\u0308gg\u00f5s\u00e9g klinikai k\u00e9p\u00e9nek h\u00e1tter\u00e9ben jellegzetes kognit\u00edv inform\u00e1ci\u00f3feldolgoz\u00e1si folyamatok felt\u00e9telezhet\u00f5k. Kutat\u00e1sunkban ezek vizsg\u00e1lat\u00e1ra a gyakorlatban \u00e9s a klinikumban egyar\u00e1nt hat\u00e9konyan alkalmazott neuropszichol\u00f3giai teszteket haszn\u00e1ltuk. Avizsg\u00e1latban 20 legal\u00e1bb 6 h\u00f3napja absztinens, de a DSM-IV szerint diagnosztiz\u00e1lt alkoholfu\u0308gg\u00f5 beteg \u00e9s 20 illesztett kontroll szem\u00e9ly vett […]<\/p>\n","protected":false},"author":4,"featured_media":50424,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"project_category":[66],"project_tag":[],"class_list":["post-49337","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-2009-en"],"_links":{"self":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project\/49337","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/comments?post=49337"}],"version-history":[{"count":9,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project\/49337\/revisions"}],"predecessor-version":[{"id":50453,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project\/49337\/revisions\/50453"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/media\/50424"}],"wp:attachment":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/media?parent=49337"}],"wp:term":[{"taxonomy":"project_category","embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project_category?post=49337"},{"taxonomy":"project_tag","embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project_tag?post=49337"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
only male premature death. Among women dissatisfaction with personal relations was the most important risk factor. Among men depression\u00a0seems to intermediate between these chronic stress factors and premature death.<\/p>\n
generalized anxiety disorder, hyperventilation syndrome, locus minoris resistentiae, milieu interieur, panic disorder, stress<\/p>\n<\/div>\n
on-line query of http:\/\/www.pubmed.gov, http:\/\/
www.clinicaltrials.gov and http:\/\/www.fda.gov,
along with an examination of poster presentations at scientific meetings held in 2008. Two
double-blind randomised clinical trials of olanzapine pamoate were conducted and demonstrate
efficacy for both the acute treatment of schizophrenia and for the maintenance of antipsychotic
response. Long-term open-label studies provide
additional information on safety.
The overall tolerability profile for olanzapine
pamoate is similar to that for the oral formulation; however, with the depot there is a risk of a
postinjection delirium sedation syndrome which
resembles an overdose of oral olanzapine and
which occurs in 0.07% of injections, requiring
patients to be observed for 3 h after injection.
At present, there are no studies available that directly compare olanzapine pamoate with other
antipsychotics other than oral olanzapine.<\/p>\n
apparently contradictory and insufficiently clarified nature of the problem halts up the systematization and exploitation of this knowledge. While
reviewing the role of serotonin in sleep regulation a special attention to the differentiation between the immediate arousing and the slowly developing circadian phase resetting and sleep
homeostatic functions of serotonin is paid. As regarding the differentiation of receptor subtypes
the article focuses on circadian rhythm and REM
regulatory\/modulatory functions in relation with
5-HT1A\/7 and 5-HT3 receptors, as well as on
sleep homeostasis, sleep intensity, ultradian
sleep organization, and sleep continuity in relation with 5-HT2A receptors. Moreover, there is
suggestive data for the reciprocal interactions between serotonin, neural plasticity and sleep spindling, which might provide new insights to the
neuropsychopharmacological characterization
of the mechanisms of action and effects of drugs
acting through the serotoninergic system.<\/p>\n
slow-wave sleep, biological clocks, circadian
rhythm, delta rhythms<\/p>\n