{"id":52894,"date":"2024-10-03T14:04:48","date_gmt":"2024-10-03T13:04:48","guid":{"rendered":"https:\/\/mppt.hu\/project\/volume-26-number-3-september-2024\/"},"modified":"2024-10-10T07:53:05","modified_gmt":"2024-10-10T06:53:05","slug":"volume-26-number-3-september-2024","status":"publish","type":"project","link":"https:\/\/mppt.hu\/en\/project\/volume-26-number-3-september-2024\/","title":{"rendered":"Volume 26, Number 3, September 2024"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.16″ custom_padding=”28px|0px|0|0px|false|false” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ custom_padding=”27px|0px|0|0px|false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.2″ header_font=”||||||||” header_text_color=”#000000″ header_4_font=”|700||on|||||” header_4_text_align=”center” header_4_text_color=”#000000″ header_4_font_size=”19px” header_4_letter_spacing=”1px” global_colors_info=”{}”]<\/p>\n

Volume 26, Number 3, September 2024<\/h3>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ specialty=”on” _builder_version=”4.16″ custom_padding=”24px|0px|25px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”3_4″ specialty_columns=”3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_row_inner _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column_inner saved_specialty_column_type=”3_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_blurb title=”Editoral in Hungarian” url=”https:\/\/mppt.hu\/magazin\/pdf\/vol26issue3\/v26i3p131.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_icon_width=”105%” content_max_width=”1100px” admin_label=”F\u00fclsz\u00f6veg” _builder_version=”4.27.2″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” custom_padding=”1px|||||” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/vol26issue3\/v26i3p131.pdf” link_option_url_new_window=”on” hover_enabled=”0″ image_max_width=”105%” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

G\u00e1bor Faludi<\/p>\n

[\/et_pb_blurb][et_pb_blurb title=”Combined Addiction and Neurobiological Targets: An In Silico Analysis of Areca Nut and Areca Nut with Tobacco Biomolecules” url=”https:\/\/mppt.hu\/magazin\/pdf\/vol26issue3\/v26i3p133.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_icon_width=”105%” content_max_width=”1100px” _builder_version=”4.27.2″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” custom_padding=”1px|||||” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/vol26issue3\/v26i3p133.pdf” link_option_url_new_window=”on” hover_enabled=”0″ image_max_width=”105%” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Anusa Arunachalam Mohandoss, Rooban Thavarajah<\/p>\n

[\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ open_icon_color=”#0c71c3″ _builder_version=”4.24.3″ title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px” global_colors_info=”{}”]<\/p>\n

Background<\/strong>: The addictive potential of areca nut (AN) and tobacco is well-documented, but their combined neurobiological effects in AN-containing tobacco products (ANTP) remain obscure. This study employed a three-stage in silico approach to investigate the potential targets and pathways associated with the addictive properties of AN alone and in ANTP.<\/p>\n

Materials and Methods:<\/strong> Bioactive molecules were retrieved for AN and tobacco, followed by target prediction and pathway enrichment analysis. The identified biomolecules were categorized into AN and ANTP groups.<\/p>\n

Results<\/strong>: A total of 195 bioactive molecules were identifid (38 to AN, 157 to tobacco). Absorption, distribution, metabolism, and excretion (ADME) details were retrieved. Predicted bioactivity (gene\/protein interaction probability \u226580%) was analysed, revealing 13 shared targets between AN and tobacco, 12 exclusive to AN, and 33 exclusive to tobacco. AN and ANTP influenced 21 and 27 pathways (FDR \u2264 0.05), respectively, with distinct footprints. Notably, GABAergic and cholinergic synapses, nicotine addiction, calcium signaling, and morphine addiction pathways were differentially enriched between AN and ANTP. Discussion: This study highlights the distinct and synergistic neurobiological effects of AN and tobacco in ANTP. The identified differences in target genes and pathways underscore the need for tailored interventions and cessation strategies for users of AN and ANTP products. Further research is warranted to validate these findings, explore interplay between diverse addiction factors, and develop effective prevention and treatment programs.
(Neuropsychopharmacol Hung 2024; 26(3): 133\u2013143)<\/p>\n

Keywords<\/strong>: Areca Nut, Tobacco, Chewing, Behavioural Addiction, Neurobiology<\/p>\n

[\/et_pb_toggle][et_pb_blurb title=”Assessing obsessive-compulsive symptoms in a subclinical and clinical sample: the development of the Hungarian version of the OCI-R” url=”https:\/\/mppt.hu\/magazin\/pdf\/vol26issue3\/v26i3p144.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_icon_width=”105%” content_max_width=”1100px” _builder_version=”4.27.2″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/vol26issue3\/v26i3p144.pdf” link_option_url_new_window=”on” hover_enabled=”0″ image_max_width=”105%” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Fl\u00f3ra F\u00fcl\u00f6p, Gyula Demeter, Ferenc Honbolyg\u00f3, Katalin Csig\u00f3<\/p>\n

[\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ open_icon_color=”#0c71c3″ _builder_version=”4.24.3″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” min_height=”39px” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px” global_colors_info=”{}”]<\/p>\n

Objectives<\/strong>: The prevalence of clinical obsessive-compulsive disorder (OCD) is around 1-2% in the population. Questionnaires, such as the OCI-R, are a useful tool in the diagnositc process. The purpose of this study was to develop the Hungarian version of the OCI-R, examine its validity and reliability, and its ability to differentiate between clinical and subclinical OCD.<\/p>\n

Methods<\/strong>: Confirmatiory factor analysis was carried out on the subclinical sample (N = 4301). Reliability analysis was carried out on both samples, and Mann-Whitney tests were used to compare the two samples.<\/p>\n

Results<\/strong>: The six-factor structure identical to the original was confirmed by confirmatory factor analysis. In the subclinical sample, all scales but Neutralizing had good reliability. Reliability analysis on the clinical sample (N = 26) showed good Cronbach\u2019s alpha values for all scales except for Hoarding. There were significant differences between the two groups on three scales: Neutralizing, Washing, and Obsessing, with the clinical group scoring significantly higher on these scales. The average score for Checking, Hoarding, and Ordering was higher in the subclinical sample, although the difference was not significant.<\/p>\n

Conclusion<\/strong>: The results highlight the advantages of symptom severity scales, such as the OCI-R, in the diagnostic process of obsessive-compulsive disorder.
(Neuropsychopharmacol Hung 2024; 26(3): 144\u2013152)<\/p>\n

Keywords<\/strong>: obsessive-compulsive disorder, subclinical sample, symptom severity scales, OCI-R<\/p>\n

[\/et_pb_toggle][et_pb_blurb title=”Clinical Pathway for Suicide Risk Screening in Adult Primary Care Settings: Special Recommendations” url=”https:\/\/mppt.hu\/magazin\/pdf\/vol26issue3\/v26i3p153.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_icon_width=”105%” content_max_width=”1100px” _builder_version=”4.27.2″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” custom_padding=”0px||0px|||” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/vol26issue3\/v26i3p153.pdf” link_option_url_new_window=”on” hover_enabled=”0″ image_max_width=”105%” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Lynsay Ayer, LIsa M. Horowitz, Lisa Colpe, Nathan J. Lowry, Patrick C. Ryan, Edwin Boudreux, Virna Little, Stephen Erban, Soett Ramirez-Estrada, Michael Schoenbaum<\/p>\n

[\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ open_icon_color=”#0c71c3″ _builder_version=”4.24.3″ title_font=”|600|||||||” title_letter_spacing=”1px” text_orientation=”justified” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px” global_colors_info=”{}”]<\/p>\n

Suicide is a serious public health concern. On average, 80% of suicide decedents had contact with primary care within one year of their suicide. This and other research underscore the importance of screening for suicide risk within primary care settings, and implementation of suicide risk screening is already underway in many practices. However, while primary care practices may be familiar with screening for other mental health concerns (e.g., depression), many feel uncomfortable or unprepared for suicide risk screening. To meet the increasing demand for evidence-based suicide-risk screening guidance, we provide a clinical pathway for adult primary care practices (to include family medicine, internal medicine, women\u2019s health). The pathway was developed by experts with research, clinical expertise and experience in suicide risk screening and primary care. We also provide detailed guidance to aid primary care practices in their decisions about how to implement the clinical pathway.<\/p>\n

Keywords<\/strong>: primary care, suicide, screening, pathway, adult, workflow<\/p>\n

[\/et_pb_toggle][et_pb_blurb title=”The Implications of Sanctions on Civilian Mental Health and Quality of life Iranian: An overview” url=”https:\/\/mppt.hu\/magazin\/pdf\/vol26issue3\/v26i3p170.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_icon_width=”105%” content_max_width=”1100px” _builder_version=”4.27.2″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” custom_padding=”1px|||||” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/vol26issue3\/v26i3p170.pdf” link_option_url_new_window=”on” hover_enabled=”0″ image_max_width=”105%” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Mohammad Tahan, Farank Azari, Tamkeen Saleem<\/p>\n

[\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ open_icon_color=”#0c71c3″ _builder_version=”4.24.3″ title_letter_spacing=”1px” text_orientation=”justified” min_height=”30px” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px” global_colors_info=”{}”]<\/p>\n

Background<\/strong>: The Islamic Republic of Iran has been under sanctions since 1979. These sanctions were further reinforced between the years 2005 and 2012. This study utilizes available data from Iran post-sanctions to review the impact of economic sanctions on both the mental health and the quality of life of Iranian citizens.<\/div>\n
\u00a0<\/div>\n
Methods<\/strong>: A comprehensive scoping review was conducted to identify studies examining the impact of sanctions on health in Iran. Searches were initiated in 2012 using PubMed\/Medline, Embase, Web of Science, Scopus, and the Scientific Information Database [Iranian Database] with keywords such as sanctions, implications, mental health, quality of life, civilian mental health, and Iran. Subsequent to the screening process, secondary reports and letters to the editor were excluded. Only original studies\u2014those collecting data via observation, interviews, surveys, experiments, or literature reviews\u2014were retained for analysis. In addition to these search strategies, reference scanning was undertaken to identify additional articles pertinent to the scope of the current study. This thorough approach facilitated the discovery of relevant and significant articles exploring the effects of sanctions against Iran on the mental health and overall well-being of its civilian population. Following the search, duplicate articles were meticulously identified and removed by the authors. Data were subsequently extracted and summarized, focusing on study characteristics and the observed effects of sanctions on civilian mental health and quality of life in Iran.<\/div>\n
\u00a0<\/div>\n
Result<\/strong>: Out of 165 items identified in the preliminary search, ten articles met the inclusion criteria. These selected articles highlighted the pronounced effects of sanctions on various health-related domains.<\/div>\n
Conclusion<\/strong>: Since 2012, Iran has been subject to intensified sanctions. There is evidence to suggest that the economic sanctions, imposed by Western nations, and have exerted a negative and detrimental impact on the health of individual Iranians.<\/div>\n
(Neuropsychopharmacol Hung 2024; 26(3): 170\u2013181)<\/div>\n
\u00a0<\/div>\n
Keywords<\/strong>: Iran sanctions, Post-sanctions data, Mental health in Iran, Sanctions implications, Economic sanctions effects, Western nations sanctions.<\/div>\n

[\/et_pb_toggle][et_pb_blurb title=”Summarising the efficiency of psychological interventions in the treatment of endometriosis” url=”https:\/\/mppt.hu\/magazin\/pdf\/vol26issue3\/v26i3p182.pdf” url_new_window=”on” image=”https:\/\/mppt.hu\/wp-content\/uploads\/2019\/04\/pdf.png” icon_placement=”left” image_icon_width=”105%” content_max_width=”1100px” _builder_version=”4.27.2″ header_font=”||||||||” header_font_size=”17px” header_line_height=”1.3em” body_font=”||on||||||” body_line_height=”1.3em” link_option_url=”https:\/\/mppt.hu\/magazin\/pdf\/vol26issue3\/v26i3p182.pdf” link_option_url_new_window=”on” hover_enabled=”0″ image_max_width=”105%” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Patricia K\u00f6rnyei-Horv\u00e1th, Szilvia Ill\u00e9s, Anna Csenki-Knyih\u00e1r<\/p>\n

[\/et_pb_blurb][et_pb_toggle title=”Abstract” closed_toggle_text_color=”#000000″ closed_toggle_background_color=”rgba(0,0,0,0)” icon_color=”#0c71c3″ open_icon_color=”#0c71c3″ _builder_version=”4.24.3″ title_letter_spacing=”1px” text_orientation=”justified” min_height=”30px” custom_padding=”0px||10px” border_width_all=”0px” border_width_bottom=”1px” global_colors_info=”{}”]<\/p>\n

Endometriosis is a common gynecological disease affecting 5-10% of women resulting in several psychological impacts. Regarding the high prevalence as well as extensive somatic symptoms, this has become a growing issue of psychological research in recent years. Thanks to its rising importance the negative effect on quality of life, mood, and anxiety symptoms has been proven. Thus we aimed to organize psychological interventions affecting the mentioned constructs and also examine their efficiency and scientific standards. Our inclusion criteria referred to studies based on randomized controlled trials, systematic reviews, and meta-analyses. We selected seven types of interventions, such as psychoeducation, cognitive behavioural therapy, mindfulness-based methods, progressive muscle relaxation, yoga, physical activity, and complex programs. Regarding the quality of life, mood, and anxiety cognitive behavioural therapy and progressive muscle relaxation were the most effective methods, however, other interventions had promising results either. Besides, there is a growing demand for psychological and mind-body interventions, which should get a more important place in the primary care of endometriosis next to medical treatment. We find inevitable further high-quality examinations, and from the point of practice, we consider it crucial to implement current evidence-based methods in the psychological care of endometriosis.<\/p>\n

Keywords<\/strong>: endometriosis, psychological interventions, quality of life, mood, anxiety, psychoeducation, cognitive behavioral therapy, mindfulness, progressive muscle relaxation, yoga, physical activity, MY-ENDO<\/p>\n

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Volume 26, Number 3, September 2024G\u00e1bor FaludiAnusa Arunachalam Mohandoss, Rooban ThavarajahBackground: The addictive potential of areca nut (AN) and tobacco is well-documented, but their combined neurobiological effects in AN-containing tobacco products (ANTP) remain obscure. This study employed a three-stage in silico approach to investigate the potential targets and pathways associated with the addictive properties of […]<\/p>\n","protected":false},"author":5,"featured_media":52745,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"project_category":[123],"project_tag":[],"class_list":["post-52894","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-2024-en"],"_links":{"self":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project\/52894","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/comments?post=52894"}],"version-history":[{"count":16,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project\/52894\/revisions"}],"predecessor-version":[{"id":52929,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project\/52894\/revisions\/52929"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/media\/52745"}],"wp:attachment":[{"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/media?parent=52894"}],"wp:term":[{"taxonomy":"project_category","embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project_category?post=52894"},{"taxonomy":"project_tag","embeddable":true,"href":"https:\/\/mppt.hu\/en\/wp-json\/wp\/v2\/project_tag?post=52894"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}